Effects of Vitamin D and Fish Oil on the Kidney in Hypertensives
Hypertension, Kidney Diseases
About this trial
This is an interventional prevention trial for Hypertension focused on measuring Hypertension, Kidney Diseases, Vitamin D, Omega 3 fatty acids
Eligibility Criteria
Inclusion Criteria:
- Participants in VITAL (NCT 01169259) with a self-reported physician diagnosis of hypertension are eligible to participate in this ancillary study
Exclusion Criteria:
- Diagnosis of diabetes mellitus
Sites / Locations
- Brigham and Women's Hospital
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Active Comparator
Active Comparator
Active Comparator
Placebo Comparator
Vitamin D and fish oil
Vitamin D and fish oil placebo
Vitamin D placebo and fish oil
Vitamin D placebo and fish oil placebo
Dietary Supplement: Vitamin D Vitamin D3 (cholecalciferol), 2000 IU per day. Drug: Omega-3 fatty acids (fish oil) Omacor, 1 capsule per day. Each capsule of Omacor contains 840 milligrams of marine omega-3 fatty acids (465 mg of eicosapentaenoic acid [EPA] and 375 mg of docosahexaenoic acid [DHA]).
Dietary Supplement: Vitamin D Vitamin D3 (cholecalciferol), 2000 IU per day. Dietary Supplement: Fish oil placebo Fish oil placebo
Drug: Omega-3 fatty acids (fish oil) Omacor, 1 capsule per day. Each capsule of Omacor contains 840 milligrams of marine omega-3 fatty acids (465 mg of eicosapentaenoic acid [EPA] and 375 mg of docosahexaenoic acid [DHA]). Dietary Supplement: Vitamin D placebo Vitamin D3 placebo
Dietary Supplement: Vitamin D placebo Vitamin D3 placebo Dietary Supplement: Fish oil placebo Fish oil placebo