Popular Diets Study
Obesity, Insulin Resistance
About this trial
This is an interventional prevention trial for Obesity focused on measuring obesity, nutrition
Eligibility Criteria
Inclusion Criteria: BMI ≥ 27 kg/m2 Willing and able to come to the GCRC 5 days per week to consume a supervised meal and pick-up food for all other meals Available for scheduled hospital admissions Willing to abstain from alcohol consumption for the duration of the study If female, regular menstrual cycles (defined as 26 to 30 days between cycles; no more than one day variation in the duration of menstrual flow) Exclusion Criteria: Weight > 350 lbs Change in body weight (± 10%) over preceding year Taking any medications or dietary supplements that might affect body weight, appetite, or energy expenditure Smoking (1 cigarette in the last week) High levels of physical activity Currently following a special diet Abnormal laboratory screening tests Type 2 diabetes mellitus Allergies or aversions to foods on the study menu Previous diagnosis of an eating disorder or any other mental health disorder If female, pregnant in the past 12 months or planning to become pregnant during the study period If female, lactating in the preceding 12 months If taking birth control medication, change in medication in previous 3 months or plans to change medication during the study period
Sites / Locations
- Children's Hospital Boston
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Active Comparator
Active Comparator
1
2
3
Low glycemic index diet
Low fat diet
Very low carbohydrate diet