
A Study of Zevalin and Simultaneous Application of BEAM High-dose Chemotherapy Followed by Autologous...
Primary Non-Hodgkin-LymphomaRefractory Non-Hodgkin-Lymphoma1 morePhase II Study Concomitant High-Dose Radio-Immuno- and Chemotherapy with simultaneous application of Zevalin and BEAM followed by autologous peripheral stem cell transplantation in relapsed and refractory CD 20+ Non-Hodgkin's lymphoma

Efficacy of Aripiprazole Versus Placebo in the Reduction of Aggressive and Aberrant Behavior in...
AutismHypothesis: (1) Aripiprazole treatment will be superior to placebo in reducing aggression and irritability in autistic individuals as shown by reductions in the Aberrant Behavior Checklist-irritability subscale. (2) Aripiprazole treatment will be superior to placebo in the acute treatment of global autism severity. The purpose of this study is to examine the possible benefit of the medication Aripiprazole in autistic individuals.

Depocyte in the Treatment of CNS Relapse in Patients With Lymphoblastic Leucemia or Very Aggressive...
Lymphoblastic LeukemiaLymphomaThe first purpose is to confirm or not the efficacy of only one administration of DepoCyte®.

Treatment for Aggression and Agitation in Patients With Alzheimer's Disease
Alzheimer's DiseaseThe purpose of this study is to determine whether this drug can help symptoms of aggression and agitation in participants with Alzheimer's disease.

Carbamazepine for the Treatment of Chronic Post-Traumatic Brain Injury Irritability and Aggression...
Traumatic Brain InjuryThe purpose of this study is to determine if carbamazepine reduces irritability and aggression among individuals with traumatic brain injury

A Phase II Study of Clofarabine in Patients With Aggressive Non-Hodgkin's Lymphoma
Non-Hodgkin's LymphomaThis study will determine the efficacy of clofarabine as measured by response rate in patients with aggressive non-Hodgkin's lymphoma

Arousal-Biofeedback for the Treatment of Aggressive Behavior in Children and Adolescents
AggressionConduct Disorder1 moreThe purpose of this study is to determine whether individualized biofeedback of arousal (skin conductance) is effective in the treatment of aggressive behavior problems in children and adolescents with either predominantly impulsive (reactive) and/or high callous unemotional traits (proactive) subtypes of aggression when compared to treatment as usual (TAU), and induces normalization when compared to a group of typically developing children receiving no intervention.

Impact of Cognitive Control Training on Anger Symptoms and Reactive Aggression
AngerHigh trait anger is a personality construct characterized by elevations in the frequency, duration, and intensity of anger episodes. According to many social cognitive theories, hostile interpretations of everyday situations contribute to the development and maintenance of anger symptoms. This study will examine the effectiveness of a computer-based cognitive control training task.

Group CBT for Aggression in Veterans
AggressionAnger1 morePosttraumatic stress disorder (PTSD) robustly predicts anger and aggression, and U.S. Iraq/Afghanistan-era combat Veterans report that treatment for anger and aggression is among their top priorities. PTSD-related anger and aggression are associated with profound functional impairments, yet to date there are no empirically-supported treatments for Veterans with PTSD and aggression. Effective group treatment programs could improve functioning and facilitate community reintegration for these Veterans. Given that anger impedes progress in treatment of PTSD symptoms, group anger treatment could also improve Veterans' capacity to benefit from individually-administered empirically-supported therapy for PTSD such as prolonged exposure or cognitive processing therapy.

Nicotinic Cholinergic Modulation as a Novel Treatment Strategy for Aggression Associated With Autism...
Autism Spectrum DisorderAggression1 moreSome individuals with autism spectrum disorders (ASD) also demonstrate irritability or aggression, which can interfere with functioning. The purpose of this pilot study is to test whether transdermal nicotine is effective for irritability and/or aggression in adults with ASD using a double-blind, placebo-controlled clinical trial. Subjects will participate in three visits. At the first visit, subjects are screened for eligibility and enrolled. Baseline measures include rating scales and a frustrative computerized task. They will then wear seven days of transdermal nicotine or placebo. Visit two is on day seven and the study measures are repeated, vital signs and side effects monitored. Subjects will return for a third and final visit on day 21 to repeat the study measures performed during visit two.