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Active clinical trials for "Contracture"

Results 31-40 of 149

Aspen™ Ultrasound System and Aspen Rehabilitation Technique in the Treatment of Capsular Contracture...

Capsular Contracture of BreastGrade III

Purpose: The purpose of this investigation is to test the safety and effectiveness of the Aspen System™ and Aspen Rehabilitation Technique. The device is intended for the therapeutic treatment of capsular contracture of the breast in conjunction with the Aspen Rehabilitation Technique. The hypothesis of the proposed study is that external ultrasound with the Aspen System™ device in conjunction with the Aspen Rehabilitation Technique is safe and effective in the reduction by at least one level of Baker Grade III capsular contracture in cosmetic breast augmentation patients, maintained at one year from the final treatment. Potential benefits of the study to subjects include improvement in the grade of capsular contracture of the breast without surgical treatment. The investigation is planned to last 12 months.

Terminated33 enrollment criteria

Ankle Equinus Contracture Treated With Dynamic Splinting

Ankle EquinusAnkle Contracture1 more

The purpose of this study is to determine if the Ankle Dorsiflexion Dynasplint System (DS) is effective in treating contracture for patients with Ankle Equinus secondary to diabetes mellitus.

Terminated15 enrollment criteria

Natural Disease Progress of Dupuytren Disease

Dupuytren ContractureDisease Progression

Dupuytren disease (DD) is a progressive fibromatosis of the palmar fascias of the hand and fingers, which may lead to extension deficits of the fingers. The disease can be very disabling in moderate and severe cases, whereby performing normal daily activities can become very problematic. The aetiology and pathogenesis are not completely understood. There is a genetic disposition and it is influenced by environmental factors. The disease is especially prevalent in white males of Northern European descent above 50 years of age. There is paucity of knowledge about the natural progression of the disease. Several studies have been conducted on progression of disease and from these studies it becomes obvious that the disease is progressive over several years. However, in most studies only one moment of follow-up has taken place, so the course of the progression over time is unknown. The aim of this study is to enhance our knowledge on the natural disease progression of DD at different stages.

Active5 enrollment criteria

Contracture Reduction Following Bunionectomy: a Longitudinal, Controlled Trial

Hallux Limitus

To determine the efficacy of Metatarsal Dynasplint Sytem (MTP) in reducing contracture of hallux limitus secondary to Bunionectomy, in a longitudinal, controlled trial.

Terminated7 enrollment criteria

Chemically Assisted Capsulectomy-A New Clinical Approach

Implant Capsular Contracture

The purpose of this study is to make available an agent,Mesna, which can assist the surgeon during the procedure of capsulectomy.

Terminated2 enrollment criteria

Safety and Efficacy of Delayed Manipulation After Xiaflex Treatment in Subjects With Dupuytren's...

Dupuytren's Disease

The purpose of this study is to determine if of manipulation of digits following collagenase injection for treatment of Dupuytren's contracture is effected by the amount of time between injection and manipulation.

Terminated6 enrollment criteria

Breast Capsular Contracture Following Post-Mastectomy Reconstruction in Women Treated With the Leukotriene...

Breast Cancer

A 2 arm, 90 patient (45 per cohort) trial in patients with breast cancer who will be undergoing mastectomy with immediate tissue-expander reconstruction to determine whether treatment with zafirlukast (20mg PO BID) can reduce or prevent the development of capsular contracture.

Terminated20 enrollment criteria

The Effect of Botulinum Toxin A Injections on Ankle Dorsiflexion Following Internal Fixation of...

Equinus Contracture

The purpose of this study is to determine if botulinum toxin type A (Botox) injections, at the time of surgery for pilon fractures, will improve ankle range-of-motion and functionality.

Terminated16 enrollment criteria

Dupuytren´s Disease Study. Primary Disease, MCP Joint, Xiapex, PNF

Dupuytren Contracture

Aim: Clinical RCT comparing functional results and recurrence rate following enzymatic treatment vs. needle aponeurotomy. Materials and methods: 30° or more contracture of only one metacarpophalangeal (MCP) joint contracture of one of the three ulnar digits and less than 20° for the adjacent proximal interphalangeal (PIP) joint. Patients with primary disease of the hand. Total of 80 patients needed to detect difference of 13.5°. 1) Needle aponeurotomy 2) Clostridium Histolyticum treatment. Clinical follow ups 1,4 weeks, 16 weeks and 1,2 and 5 years. Functional outcome scores: URAM, Quick Dash, EQ5D, brief MHQ, VAS pain and VAS patient satisfaction. Total passive extension contracture reduction, recurrence rate and registration of complications.

Completed13 enrollment criteria

The Posttraumatic Elbow Stiffness Treatment

Elbow Joint ContractureElbow Flexion Contractures2 more

This study compares patients with post traumatic elbow stiffness and evaluate the range of motion improvement with two types of treatment: surgical release versus non-surgical rehabilitation protocol with orthoses.

Completed22 enrollment criteria
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