Use of Metabolomics to Differentiate the Antihypertensive Effect of Acupuncture From Sham Acupuncture...
Hypertension,EssentialTo assess the effect of acupuncture versus sham acupuncture on regulating the targeted metabolome of hypertensive patients.
A Study to Evaluate the Effect of Fimasartan on Pharmacokinetics, and the Safety of Digoxin in Healthy...
Essential HypertensionThe purpose of this study is to evaluate the effect of fimasartan on pharmacokinetics, and the safety of digoxin.
A Clinical Trial to Compare and Evaluate the Pharmacokinetic Characteristics and the Safety of Fimasartan...
Essential HypertensionHepatic ImpairmentTo compare and evaluate the pharmacokinetic characteristics and the safety of fimasartan in hepatic impairment patients and healthy volunteers
The Effect of Eprosartan on Hormones and Kidney Function in Patients With Essential Hypertension...
Essential HypertensionWe, the investigators at Holstebro Hospital, want to test the hypothesis that eprosartan reduces the activity of the sympathetic nervous system in patients with essential hypertension - during baseline conditions and after activation of the sympathetic nervous system.
Vedic Medical Astrology in Essential Hypertension
Essential HypertensionPrevious studies have explored the correlation and impact of astrological events in relation of diseases, health concerns and relationship between birth chart and disease risk. Cardiovascular conditions, sleep and fertility were found significantly associated with moon phase. However, to best of our knowledge no study has documented the impact of astrological intervention in disease management. This is a randomised, multi-center, double blind placebo controlled clinical trial with two parallel arms. This trial aims to evaluate the effectiveness of Vedic medical astrological intervention for patients with mild to moderate hypertension,with respect to decreasing their blood pressure and improving their quality of life.
Licorice and Home Blood Pressure
Hypertension,EssentialOut-of-office blood pressure is more strongly associated with cardiovascular risk than office blood pressure. Licorice is known to raise blood pressure, but no previous studies have measured the effects on home blood pressure. The aim of this study is to analyze the association between licorice intake and home blood pressure.
Effectiveness of SMS Reminders of Blood Pressure-lowering Drugs Intake
HypertensionPrimary Hypertension4 moreBy conducting the SPPA trial we try to find out, whether personalized Short Message Service (SMS) reminders of blood pressure-lowering medication can effectively increase patients' adherence to blood pressure-lowering medication. Additionally, we also evaluate their effect on patients' systolic blood pressure control.
Study of the Product QGC001 as a Single Dose and Multiple Doses Administered Orally to Healthy Adult...
Essential Hypertension1QG2 is a Phase 1 study aiming to assess the safety and tolerability of ascending single/multiple oral doses (SAD & MAD) in healthy young subjects, the preliminary food interaction and the effect of QGC001 on blood pressure and heart rate, but also to determine pharmacokinetic preliminary profiles of QGC001 and its metabolite EC33 and pharmacodynamic preliminary profiles of QGC001 and its metabolite EC33 especially effects on the renin-angiotensin-aldosterone and copeptin systems.
Fimasartan (BR-A-657) Multiple Oral Dose in Healthy Subjects
Essential HypertensionThe objective of this study is to determine the safety and tolerability and to determine the Pharmacokinetic and Pharmacodynamic(PK/PD) of ascending multiple oral dose of BR-A-657 in healthy male subjects.
A Study to Evaluate the Effect of Ketoconazole and Rifampicin on the Pharmacokinetics of Fimasartan...
Essential HypertensionTo evaluate the effect of ketoconazole and rifampicin on the pharmacokinetics of fimasartan.