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Active clinical trials for "Dry Eye Syndromes"

Results 361-370 of 976

A Phase 4 Study Investigating the Efficacy of Retaine™ in Managing Signs and Symptoms Associated...

Keratoconjunctivitis Sicca

This study will evaluate the efficacy of Retaine™ ophthalmic emulsion in treating the signs and symptoms of dry eye syndrome.

Completed13 enrollment criteria

Safety and Efficacy of rhNGF Eye Drops at Different Doses in Patients With Dry Eye

Dry Eye Syndrome

The primary objective of this study was to assess the efficacy and safety of different doses of rhNGF when administered as eye drops to patients with dry eye.

Completed20 enrollment criteria

Changes in Tear Osmolarity Over Time With Sustained Use of TheraTears

Dry Eye Syndrome

The objective of the study is to see if there is a change in tear osmolarity over time when moderate to severe dry eye subjects are treated with TheraTears® lubricating drops.

Completed16 enrollment criteria

A Safety and Efficacy Study of OPTIVE FUSION™ With VISMED® Multi for the Management of Dry Eye

Dry Eye SyndromesKeratoconjunctivitis Sicca

This study will evaluate the safety and efficacy of OPTIVE FUSION™ compared to VISMED® Multi for the management of dry eye.

Completed6 enrollment criteria

IPL and Meibomian Gland Expression to Treat Ocular Rosacea Ocular GVHD

GVHDOcular Rosacea1 more

The purpose of this study was to see if Intense Pulsed Light (IPL) can be used safely and effectively to help treat dry eyes from ocular rosacea after chronic graft-versus-host disease (GVHD). Current treatment options for this disease are limited.

Completed6 enrollment criteria

Tolerability, Safety and Efficacy of Lubricin Eye Drops vs Sodium Hyaluronate Eye Drops in Subjects...

Dry Eye SyndromeTear Film Insufficiency

Dry eye is a multifactorial disease of the tears and ocular surface that results in symptoms of discomfort, visual disturbance, and tear film instability with potential damage to the ocular surface. It is accompanied by increased osmolarity of the tear film and inflammation of the ocular surface. Lubricin is a mucin-like glycoprotein originally discovered in synovial fluid, as a secreted product of cells that line the joint tissues, which is present at the surface of articular cartilage and it has been investigated on its roles at the ocular surface, in normal and pathologic conditions such as dry eye. The objective of the study is to assess the tolerability, safety and efficacy of Lubricin eye drops solution administered over 4 weeks versus sodium hyaluronate (Na-HY) eye drops solution in subjects with moderate dry eye.

Completed23 enrollment criteria

Safety Study of Lifitegrast to Treat Dry Eye

Dry Eye Disease

The purpose of the study is to evaluate the safety of lifitegrast ophthalmic solution compared to placebo in the treatment of dry eye as assessed by ocular and non-ocular adverse events when administered BID for approximately 1 year.

Completed14 enrollment criteria

Efficacy and Safety of Rebamipide in Subjects With Dry Eye Syndrome

Dry Eye Syndrome

The purpose of this study is to evaluate the efficacy and safety of rebamipide ophthalmic suspension in subjects with dry eye syndrome.

Completed8 enrollment criteria

Clinical Evaluation of Systane® ULTRA Compared to OPTIVE® in Ocular Surface Staining

Dry Eye Syndrome

The purpose of this study is to compare Systane® ULTRA lubricant eye drops to OPTIVE® lubricating eye drops for ocular surface staining within dry eye subjects and to evaluate the safety of Systane® ULTRA after 3 months of use.

Completed10 enrollment criteria

Efficacy and Safety of HU007 Eye Drops in Patients With Dry Eye Syndrome

Dry Eye Syndrome

A multicenter, Randomized, Double blind, Restasis®-controlled Non-inferiority, Moisview® Eye Drops-controlled Superiority, Phase III Study to Evaluate the Efficacy and Safety of HU007 Eye Drops in Patients with Dry Eye Syndrome

Completed8 enrollment criteria
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