Nanofat on Wound Healing and Scar Formation
ScarsDelayed Wound Healing3 moreThis study will evaluate the effectiveness and safety of intradermal injection of Nanofat on wound healing and scar formation.
Efficacy & Safety of Clindamycin and Tretinoin in Acne
AcneThe purpose of this study is ascertain the efficacy and safety of Clindamycin Phosphate 1.2% and Tretinoin 0.025% in the treatment of Acne and Post Inflammatory Hyperpigmentation in patients with skin of color.
Can Intravenous Vitamin C Improve Skin Hyperpigmentation in Long-Term Hemodialysis Patients?
Kidney FailureChronicIntravenous vitamin C may improve skin hyperpigmentation in chronic hemodialysis patients
An In Vivo Model for Postinflammatory Hyperpigmentation
Post-inflammatory HyperpigmentationPost-inflammatory hyperpigmentation (PIH) is an acquired hypermelanosis that occurs after cutaneous inflammation or injury that frequently affects darker skinned populations. Previously, a model of 35% TCA-induced PIH was validated against acne induced PIH, which has value in product testing for the treatment of PIH. In this second phase of the study, the investigators would like to determine if a lower concentration of TCA-induced PIH is comparable to acne-induced PIH.
In Vivo Imaging of Pigmentary Disorders by Reflectance Confocal Microscopy
VitiligoMelasma2 moreThis is a pilot study to evaluate the findings of the Reflectance Confocal Microscopy when performed in cutaneous pigmentary disorders, such as vitiligo, melasma, post-inflammatory hyper-pigmentation and hypo-pigmentation. Confocal Microscopy is a recent diagnostic technique that has been used for observation of skin conditions that affect the superficial layers of the skin.
A Study to Determine the Safety & Efficacy of Autologous Human Platelet Lysate (HPL) in Treatment...
Periorbital Hyperpigmentation (Dark Circles)This is a multicentre, open label, randomized, pilot study to evalute safety and efficacy of Human Platelet Lysate (HPL) in subjects with Periorbital Hyperpigmentation. The study is being conducted at 2 centers in India.The primary endpoints are Physicians and Patient Self assessment score. The secondary endpoints are improvement in photographic assessment form randomization to end of study.
A Combination Treatment Reduces Acne Severity and PIHP
AcnePostinflammatory HyperpigmentationAcne is a chronic, inflammatory skin condition. It may cause scars and post-inflammatory hyperpigmentation (PIHP). PIHP frequently affects individuals with a phototype of IV or above.[1] PIHP is worsened by UV radiation, lasts for years and impacts the individual well-being.[2, 3] In an observational study, 1785 adults with a phototype ranging from IV to VI with acne and PIHP applied daily for 2 months a dermocosmetic and a tainted sunscreen product (DC, Effaclar® Duo (+); SS, Anthelios® Shaka Fluide SPF 50+, SS; both La Roche-Posay Laboratoire Dermatologique, France.
Identification of Gene Biomarkers in Aging Skin
HyperpigmentationSkin AgingThis study is a blinded, prospective, single-center, clinical study conducted in Japanese female subjects between the ages of 20-75 years. This design uses skin biopsy samples from environmentally exposed areas and unexposed (control) areas within the same subjects to assess the gene expression profile from three different age groups.
Physiopathologic Aspects and Quality of Life in Participants With Eye Dark Circles
Periorbital HyperpigmentationThis study will evaluate the physiopathologic characteristics of dark circles in participants with various ethnicities and Fitzpatrick Skin Types and the impact of the dark circles on the quality of life.
Clinical, Histological and Biochemical Characterization of Hyperpigmented Lesion
LentigoMelasmaHypothesis - The developments of solar lentigine and melasma are due to mutations in keratinocytes that drive the production and transfer of pigment from melanocytes to keratinocytes.