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Active clinical trials for "Marijuana Use"

Results 31-40 of 52

An Effectiveness Trial of Project ALERT

Alcohol DrinkingSmoking1 more

The purpose of this study is to replicate a longitudinal evaluation of Project ALERT, a substance abuse prevention program that targets middle school students.

Completed5 enrollment criteria

Helping Eliminate Marijuana Use Through Pediatric Practice

Marijuana

This study adapts the Public Health Service (PHS) 5As model for use with adolescent marijuana users and pilot the intervention to test feasibility and acceptability in pediatric primary care settings. The specific aims are as follows: Aim 1: Develop a marijuana screening and brief counseling intervention for adolescents based on the Public Health Service 5As model and previously developed adolescent smoking cessation intervention. Hypothesis 1: The 5As model can be adapted for use as a marijuana screening and counseling intervention for adolescents. Aim 2: Test the feasibility and acceptability of the 5As marijuana screening and brief counseling intervention in pediatric primary care practice. Hypothesis 2a: Pediatric clinicians will find the 5As intervention feasible and acceptable for addressing marijuana use in routine clinical visits with adolescents and their families; and Hypothesis 2b: Adolescents will find the 5As intervention delivered by their clinicians to be acceptable in the context of routine preventive services delivery.

Completed7 enrollment criteria

A Clinical Trial of SBIRT Services in School-based Health Centers

Marijuana UseAlcohol Consumption2 more

The purpose of the study is to examine the comparative effectiveness of a computerized brief intervention vs. an in-person brief intervention delivered by a nurse in reducing marijuana, alcohol, and sex risk behaviors in adolescents receiving services in school-based health centers.

Completed6 enrollment criteria

Laboratory Study of Cannabidiol on the Effects of Smoked Marijuana

SmokingMarijuana

The objective of this study is to assess the effects of oral cannabidiol (CBD; 0, 200, 400, 800 mg) on smoked marijuana's (0, 5.6% THC) subjective, reinforcing, cognitive, and cardiovascular effects. This experiment is expected to reveal CBD's intrinsic effects when combined with placebo marijuana, as well as its ability to modulate the behavioral effects of active marijuana.

Completed12 enrollment criteria

Effects of Low-dose Naltrexone in Combination With a Range of Smoked Marijuana

Marijuana Smoking

In heavy marijuana smokers, opioid receptor blockade increases the subjective and cardiovascular effects of marijuana. The current study was designed to clarify opioid-cannabinoid interactions by assessing how naltrexone shifts the dose-response function for marijuana-elicited effects in heavy marijuana smokers. For this within-subject, double-blind study, a marijuana smoking procedure was designed to characterize a dose-response relationship for marijuana's subjective and cardiovascular effects under blinded conditions.

Completed5 enrollment criteria

Project Chill: Tailored Youth Drug Intervention In Primary Care

Marijuana Use

This study examines the impact of tailored computer-delivered and therapist-delivered brief motivations prevention/interventions both for adolescents who have not initiated marijuana use (prevention), and those who use marijuana (intervention). Key moderators of prevention/intervention effectiveness will be examined, including behavioral intentions, self-efficacy, stage of change, school involvement, susceptibility to peer pressure, and potential health consequences such as STD/HIV risk behaviors. This project will provide the critical first step toward the development and implementation of marijuana use prevention/intervention programs that have the potential to be delivered to a large segment of youth who seek care in our nation's primary care settings.

Completed9 enrollment criteria

Behavioral Economic Analysis of Demand for Marijuana

Marijuana Smoking

This laboratory study will employ a multi-session experimental design to examine the behavioral economic demand for marijuana, by studying effect of marijuana administration (High THC) on demand for marijuana, and marijuana smoking topography. The study will recruit 100 non-treatment seeking marijuana users who smoke marijuana at least twice weekly.

Completed16 enrollment criteria

Effect of Quetiapine on Marijuana Withdrawal and Relapse

Marijuana Smoking

The objective of this study is to investigate the interaction between marijuana and quetiapine, with the goal of using this information to improve marijuana treatment outcome.

Completed15 enrollment criteria

Effects of a Range of Naltrexone Doses in Combination With Smoked Marijuana

Marijuana Use

The purpose of this study is to determine if the subjective effects of marijuana will be decreased by low-doses (< 25 mg) of naltrexone and increased by high-doses (> 50 mg) of naltrexone.

Completed14 enrollment criteria

Effects of Smoked Marijuana on Risk Taking and Decision Making Tasks

Marijuana Use Disorder

The purpose of this study is to investigate the effects of smoked marijuana on both risk taking and decision making tasks.

Completed14 enrollment criteria
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