Sensorimotor Training Versus Resistance Training in Patients With Knee Osteoarthritis
Knee OsteoarthritisPeople with knee osteoarthritis (OA) have functional instability and defective neuromuscular function, it was recently suggested that sensorimotor exercises may be important and needed to improve the effectiveness of training programs for these patients. This study objective was to compare the effectiveness of a supervised resistance muscular training (RT) versus sensorimotor training (SMT) for patients with Knee OA, on decrease of pain and functional improvement.
Active Drug Comparative, Multi-center, phase3 Clinical Study to Evaluate the Efficacy and Safety...
Osteoarthritis of the KneeThe objective of this study was to to evaluate the efficacy and safety of PG201 in osteoarthritis patients. This clinical study was designated to be non-inferiority test with level of significance: 95%, α=0.05. Type 2 error (β) was set as 0.2, and the power of the test was set as 80%. Assuming 20% drop-out rate, the number of subjects required for each treatment group was estimated to be 154, while the total number of subjects required for the study 308. non-inferiority margin: 8mm
The Effects of Collateral Meridian Therapy for Knee Osteoarthritis Pain Management
Knee OsteoarthritisPainCollateral meridian therapy (CMT) is a recently developed technique according to traditional Chinese medicine (TCM) experiences, differing from traditional Chinese acupuncture in numerous manners. CMT involves the manipulation of a distant non-painful collateral meridian, thereby facilitating the dissipation of pain. The technique avoids direct stimulation of the involved meridian, which enhances patient tolerability and prevents further injury to the disease and painful areas. Numerous clinical cases have reported the effectiveness of CMT in pain management. This study tests whether CMT is effective for treating knee OA pain and functional recovery.
A Study to Access the Efficacy and Safety of Meloxicam in Patients With Osteoarthritis of the Knee...
OsteoarthritisTo Access the Efficacy and Safety of Meloxicam 7.5mg once daily over a treatment period of 56 days
Biomarkers and Knee Osteoarthritis
Knee OsteoarthritisHigh joint load during walking has been linked to cartilage degradation. Biomarkers, found in the blood and urine, are protein fragments released after cartilage degradation characteristic of OA. They have the potential to enable direct and immediate disease state monitoring and identification of early cartilage changes. Little is known about the association of biomarkers with joint load or if exercise aimed at reducing joint load changes biomarker levels, thus reducing the risk of OA progression. This study will provide novel information on these relationships and will guide future intervention studies. The investigators hypothesize that certain biomarkers will be highly correlated with joint loading during walking and that the levels of these biomarkers in the blood and urine will decrease following an exercise intervention aimed at cartilage unloading.
Complex Āyurvedic Treatment in Osteoarthritis of the Knee Compared to Standard Care.
OsteoarthritisThe aim of this study is to evaluate the effectiveness of a complex āyurvedic diagnosis and treatment compared to conventional standard care in patients with OA of the knee.
Autologous Adipose Tissue Derived Mesenchymal Stem Cells Therapy for Patients With Knee Osteoarthritis...
Knee OsteoarthritisTwo injections in total and 3 ml autologous adipose-tissue-derived stem cells(haMSCs) for each injection; time-points for intervention: 1) initial injection; 2) 3 weeks following initial injection.
Intra-articular Corticosteroid Injection Compared With Single-Shot Hyaluronic Acid for Treatment...
Knee OsteoarthritisCorticosteroid and Hylan G-F 20 are both effective in improving pain and function of osteoarthritic knee patients.
Corticospinal Excitability and Rehab in Knee Osteoarthritis
Knee OsteoarthritisTo determine differences in thigh muscle function in individuals with and without knee arthritis, and also determine the effectiveness of common physical therapy interventions on clinical and patient oriented outcomes.
Cabbage Leaf Wraps in Osteoarthritis of the Knee
Osteoarthritis of the KneeThis randomised controlled trial aims to investigate the efficacy of cabbage leaf cataplasms in the treatment of primary symptomatic osteoarthritis of the knee. 81 patients will be randomised into one of 3 groups and apply either cabbage leaf cataplasm or diclofenac gel daily for 4 weeks or receive only usual care. Efficacy will be measured using questionnaire on pain, disability, quality of life and pressure pain sensitivity.