Study Assessing Effects of JZP-110 on Driving Performance in the Treatment of Excessive Sleepiness...
NarcolepsyExcessive SleepinessThis trial is a randomized, double-blind, placebo-controlled, crossover study to evaluate the effect of JZP-110 on driving performance in subjects with excessive sleepiness due to narcolepsy.
Study Assessing Effects of JZP-110 on Driving Performance in the Treatment of Excessive Sleepiness...
Obstructive Sleep ApneaExcessive SleepinessThis trial is a randomized, double-blind, placebo-controlled, crossover study to evaluate the effect of JZP-110 on driving performance in subjects with excessive sleepiness due to obstructive sleep apnea.
A Study of the Safety and Effectiveness of ADX-N05 in the Treatment of Excessive Daytime Sleepiness...
NarcolepsyThis is a study to evaluate the safety and effectiveness of ADX-N05 compared to placebo in the treatment of excessive daytime sleepiness in adults with narcolepsy.
Efficacy and Safety Study of BF2.649 and BF2.649 Add on Modafinil on Cataplexy in Patients With...
NarcolepsyCataplexy1 moreThe objective of this study is to evaluate and compare the efficacy and safety of escalating doses of BF2.649 and BF2.649 add on Modafinil on cataplexy in patients with narcolepsy
Efficacy and Safety of BF2.649 in Excessive Daytime Sleepiness (EDS) in Parkinson's Disease
Parkinson's DiseaseTo compare the efficacy of BF2.649 over placebo (12 week Double-Blind Phase) and assess the long term safety and the efficacy maintenance(9 months Open-Label Extension Phase) of BF2.649 in the improvement of excessive daytime sleepiness in patients diagnosed with Parkinson's Disease.
Efficacy and Safety of Armodafinil for Adults With Excessive Sleepiness Obstructive Sleep Apnea/Hypopnea...
Sleep DisordersObstructive Sleep Apnea2 moreThe primary objective of the study is to evaluate whether armodafinil at a target dosage of 200 mg/day is more effective than placebo treatment in improving excessive sleepiness in patients with obstructive sleep apnea/hypopnea syndrome (OSAHS) who have comorbid major depressive disorder or dysthymic disorder.
Use of Armodafinil for Fatigue in Sarcoidosis
SarcoidosisFatigue1 moreTo determine the effect of Armodafinil (Nuvigil) on fatigue and sleep in sarcoidosis.
VSF-173 Study in Healthy Adult Volunteers for Treatment of Induced Excessive Sleepiness
Excessive SomnolenceThe purpose of this study is to determine the safety and efficacy of VSF-173 compared to placebo in treatment of induced excessive sleepiness.
Sedating Antidepressant Improves Driving Safety in Patients With Major Depressive Disorder
DepressionExcessive Daytime SleepinessThis concurrent, two-part study will: I) Using overnight sleep recordings, evaluate the short- and long-term sleep-promoting effects of the antidepressant mirtazapine (Remeron) in patients who have been prescribed this medication for major depressive disorder and sleep disruption. II) Investigate the psychomotor performance of depressed patients using driving simulation testing before and during treatment with mitrazapine.
Assess the Safety and Effectiveness of PROVIGIL Treatment in Children and Adolescents With Excessive...
NarcolepsyThe primary objective of the study is to evaluate the safety and tolerability of treatment with PROVIGIL in children and adolescents with excessive sleepiness (ES) associated with narcolepsy or obstructive sleep apnea/hypopnea syndrome (OSAHS), when administered for up to 6 months.