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Active clinical trials for "Spinal Diseases"

Results 161-170 of 242

The Effect of AposTherapy on the Level of Pain, Function and Quality of Life in Patients With Neuro-muscular...

OsteoarthritisSpinal Diseases3 more

The purpose of the study is to examine the effect of a new biomechanical device and treatment methodology (AposTherapy) on gait patterns, pain, function and quality of life of patients with musculoskeletal and neurological disorders. Based on previous reports the investigators hypothesis that this therapy will have a positive effect on these measurements.

Unknown status8 enrollment criteria

Freedom Lumbar Disc in the Treatment of Lumbar Degenerative Disc Disease

Degenerative Disc Disease (DDD)

This study will look at the result of using the FLD device as an artificial lumbar disc. The study will compare the safety and effectiveness of the FLD artificial lumbar disc to an already approved artificial lumbar disc.

Unknown status38 enrollment criteria

Indirect Approach of C0-1 and C2-3 Segments in Flexion-rotation Test

Neck PainCervical Spine Disease1 more

Restrictions on upper cervical spine are associated with cervical pain. The vast majority of upper cervical spine rotation occurs at the C1-2 segment. Flexion-rotation test is a valid measure that predominantly measures rotation in C1-2 segment, however upper cervical spine rotation also implies C0-1 and C2-3 due to ligament anatomy. Restriction in flexion-rotation may be due to direct restriction in C1-2, but also to a premature tightening of the alar ligament as a result of lack of movement in C0-1 or C2-3. The objective is to compare the effect of a 20-minutes single cervical exercise session with or without manual therapy of C0-1 and C2-3 segment in flexion-rotation test in patients with chronic neck pain and positive flexion-rotation test. To carry out the objective, the following will be designed a randomized controlled assessor-blind clinical trial with primary healthcare patients. This population will be patients with chronic neck pain and positive flexion-rotation test. These patients will be assigned in manual therapy + exercise group or in exercise group. Exercise will be focused on deep anterior cervical muscles. Manual therapy will combine techniques in C0-1 and C2-3 with this exercise. Flexion-rotation test, neck pain intensity, pain intensity during the flexion-rotation test and cervical range of motion will be measured before and after the intervention.

Unknown status12 enrollment criteria

Total Facet Arthroplasty System®(TFAS®) Clinical Trial

Spinal StenosisLow Back Pain4 more

The Archus Total Facet Arthroplasty System® (TFAS®) is a non-fusion spinal implant indicated for treatment of patients with moderate to severe spinal stenosis. TFAS® replaces the diseased facets following surgical removal. TFAS® offers the surgeon new options for treating spinal stenosis patients, enabling a more comprehensive decompression via complete removal of the facets. TFAS® also offers an alternative to rigid spinal fusion fixation enabling intervertebral motion. The clinical trial is intended to demonstrate restoration of stability and sagittal balance to the spine. TFAS® also eliminates the need for painful bone graft harvest from the patient's hip which may be required with fusion procedures.

Unknown status21 enrollment criteria

Freedom® Cervical Disc Use In The Treatment of Cervical Degenerative Disc Disease

Symptomatic Cervical Degenerative Disc Disease (DDD) From C3-C7

This study will collect clinical and radiographic data on the Freedom Cervical Disc to monitor the device's safety and performance as part of a post-market evaluation.

Unknown status20 enrollment criteria

The Effect of Perioperative Lidocaine Intravenous Infusion on Postoperative Recovery After Spine...

Spinal Diseases

The purpose of this study is to evaluate the effectiveness of perioperative Lidocaine intravenous infusion in reducing postoperative pain for spine surgery patients.

Unknown status4 enrollment criteria

Optimization of a Tool for Predicting Postoperative Clinical Evolution After Lumbar Surgery

Spine DiseaseSpinal Fusion2 more

The objective of the study is the establishment, optimization and prospective evaluation of a digital predictive platform capable of providing for each lumbar spine operated patient a clinical predictive status: Patient green (success) orange (treatment failure ), red patient (complication) in order to optimize his medical care up to 6 months.

Completed10 enrollment criteria

The Diagnostic and Prognostic Value of Two Quantitative Clinical Tests in Patients With Lumbar Disc...

PainLumbar Disc Herniation3 more

This study will investigate whether two clinical tests can be used to diagnose and predict the outcome in patients with lumbar disc herniation undergoing surgery and non-surgery treatment. The two quantitative clinical tests include: electromyographic measurements using Paraspinal Mapping and pain responses using Quantitative Sensory Pain Testing.

Completed8 enrollment criteria

Validation of the Utility of an Artificial System for the Large-scale Screening of Scoliosis

Orthopedic Disorder of SpineArtificial Intelligence1 more

Traditional school scoliosis screening approaches remains debatable due to unnecessary referal and excessive cost. Deep learning algorithms have proven to be powerful tools for the detection of multiple diseases; however, the application of such methods in scoliosis screening requires further assessment and validation. Here, the investigators develop an artificial system for the automated screening of scoliosis using disrobed back images, and conduct clinical trial to validate if the diagnostic system can offsetting the shortcomings of human doctors.

Completed2 enrollment criteria

Perfusion and Diffusion Mechanism of Intervertebral Disc-Significance With Age, Degeneration, Posture...

Spinal Cord InjuryDegenerative Spinal Disease.

The purpose of our study is to evaluate the perfusion of the IVDs and their diffusion ability by using the Dynamic contrast-enhanced MR perfusion technique and Diffusion weighted image with ADC value measurement, and to determine the relationship between these data and the degeneration of IVDs, the different posture, and different stress-loading status.

Completed3 enrollment criteria
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