Temporomandibular Joint Arthrocentesis With Infiltration of PRP + Ropivacaine Versus PRP
Temporomandibular Joint DisordersThe infiltration of Platelet Rich Plasma (PRP) at the end of Temporomandibular Joint (TMJ) arthrocentesis is already an established procedure in the treatment of Temporomandibular Disorders (TMD). Arthrocentesis is a minimally invasive surgical procedure, which aims to eliminate the inflammatory mediators from the inside of the TMJ. PRP is an autologous concentrate of platelets and growth factors, derived from centrifugated blood. Several studies have described the benefits of PRP: it enhances wound healing because of the presence of cytokines and growth factors, and is also stimulates chondrocytes to biosynthesis of collagen. Ropivacaine is a local anesthetic that has been synthesized for use in infiltration anesthesia and to produce both peripheral and central block. Unlike one of its analogues, Bupivacaine, Ropivacaine anesthetize the sensory fibers without affecting the motor ones. The main goal of this investigation is to test the benefits of adding Ropivacaine to the infiltration of PRP in patients submitted to TMJ arthrocentesis.
Neural Mechanisms of Immersive Virtual Reality in Chronic Pain
PainVirtual Reality2 moreThis project examines, in chronic pain, the mechanisms of immersive virtual reality compared to the mechanisms of placebo hypoalgesia. The potential of developing new non-pharmacological premises for low-risk interventions for pain management is high.
The Effect of Opioid-Free Anesthesia in TMJ Surgery
Temporomandibular Joint DisordersThis study aims is to evaluate the effect of opioid free total intravenous anesthesia on postoperative quality of recovery in patients undergoing oral and maxillofacial surgery (OMF) temporomandibular joint (TMJ) surgery.
Effectiveness of Physiotherapy Treatments in Temporomandibular Joint Dysfunction
PainTemporomandibular Joint Disorders5 moreThe study will determinate the influence of four selected physiotherapeutic procedures on the pain intensity, the bioelectrical activity of the masseter muscle, and the range of mandibular mobility in patients with TMDs (temporomandibular joint dysfunction).
Characteristics of Cytokine Response in Patients With Temporomandibular Disorders Treated With Occlusal...
Temporomandibular Joint DisordersThe goal of this intervention study is to determine the effect of occlusal splint (OS) therapy on the concentration of inflammatory cytokines in serum and gingival crevicular fluid (GCF) in patients with temporomandibular disorders (TMDs). Aims are: to determine cytokines level in GCF and serum before and after OS therapy to determine the degree of psychosocial dysfunction and oral health-related quality of life before and after OS therapy investigate the correlation between cytokines level in GCF and serum to determine the effect of OS on treatment outcomes, pain intensity, dysfunction, and psychosocial status of patients with painful TMD. Participants will be asked to complete self-assessment questionnaires, and GCF and blood samples will be collected before beginning of the OS therapy and at follow-up examinations one month and two months after.
Safety and Efficacy of Erenumab-aooe in Patients With Temporomandibular Disorder
Temporomandibular DisorderThe purpose of this proof of concept study is to evaluate the safety and efficacy of the off-label use of Aimovig® (EREN) in reducing Temporomandibular Disorder (TMD) pain compared to placebo.
Effcet of Temporomandibular Joint Disorder Relaxation and Myofacial Relaxation Techniques on Tension...
Tension-Type HeadacheThe aim of this course is to investigate the effect of temporomandibular joint relaxation and myofacial relaxation techniques on quality of life , Joint range of motion, headache, depression in individuals with tension type headache.
Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia
DystoniaDrug Induced Dystonia9 moreThis research involves retrospective and prospective studies for clinical validation of a DystoniaNet deep learning platform for the diagnosis of isolated dystonia.
Impact of Orthodontic Treatment on the Temporomandibular Joints (TMJ) Assessed by Modjaw
Temporomandibular Joint DisordersThe aim of the study is to assess the correlation between orthodontic treatment and temporomandibular joint (TMJ). For that, an evaluation with a virtual articulator (Modjaw) is carried out before and after the treatment. The condylar course are compared. Furthermore, the eventual TMJ symptoms are also compared before and after.
Application of a Dental-dedicated MRI in the Diagnosis of Temporomandibular Joint Disorders, Tissue...
TMJApical Periodontitis3 moreThe aim of the present study is to show that the use of 0.55T MRI combined with a "dental" coil produces images of sufficient diagnostic value to assess areas of interest in dentistry, and to compare MR images to traditional, dental-oriented radiographic images for diagnostic purposes.