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Active clinical trials for "Torticollis"

Results 51-60 of 120

Clinical Trial to Compare the Safety and Efficacy of Botulax® Versus Botox® in Patients With Cervical...

Cervical Dystonia

To determine the efficacy and safety of Botulax® in treatment of cervical dystonia

Completed5 enrollment criteria

Dose-escalating Safety and Preliminary Efficacy of DaxibotulinumtoxinA for Injection in Cervical...

Torticollis (Spasmodic)

This is an open-label, dose-escalation study to assess the safety and preliminary efficacy of daxibotulinumtoxinA in subjects with isolated cervical dystonia (CD).

Completed13 enrollment criteria

Study Comparing Short Term Efficacy of Dysport and Dysport NG to Placebo, and to Assess Efficacy...

Cervical Dystonia

The purpose of this study is to evaluate how well a new drug called Dysport NG works and how safe it is, when it is used for the treatment of cervical dystonia. Dysport NG will be compared to an approved drug called Dysport.

Completed10 enrollment criteria

Open-Label Non-Inferiority Study Evaluating the Efficacy and Safety of Xeomin® in Subjects With...

Cervical Dystonia

This study will compare Xeomin®, a botulinum toxin medication, in shorter treatment intervals (Short Flex dosing) to the standard interval dosing (Long Flex dosing) to determine if the response to treatment is comparable in both how it works and any side effects. Xeomin® is approved by the United States Food and Drug Administration (FDA) for the treatment of cervical dystonia (CD). The use of Xeomin® is investigational in regards to shorter treatment intervals. An investigational use is one that is not approved by the FDA.

Completed2 enrollment criteria

Study to Assess the Efficacy and Safety of Dysport® in Cervical Dystonia

Cervical Dystonia

The aim is to demonstrate equivalent efficacy and safety in the treatment of the two most frequent forms of cervical dystonia (predominantly rotational torticollis and predominantly laterocollis) with the standard initial dose of 500 units Dysport®. The patients will be assigned to one of the two basic types of cervical dystonia, either predominantly rotational torticollis or predominantly laterocollis on the basis of clinical examination. This will determine which therapy is to be administered, using the clearly defined, structured injection protocols.

Completed8 enrollment criteria

Effect of Botulinum Toxin Type A on Swallowing in Patients With Cervical Dystonia

Torticollis

The purpose of this study is to evaluate swallowing efficiency in patients with cervical dystonia following treatment with botulinum toxin Type A.

Completed5 enrollment criteria

Comparison of Efficacy and Safety of Two Different Types of Botulinum Toxin Type A in Moderate to...

Spasmodic Torticollis

The purpose of this study is to compare two types of botulinum toxin type A to treat the involuntary muscle contractions in the neck

Completed5 enrollment criteria

IncobotulinumtoxinA (Xeomin) Versus Placebo in the Treatment of Cervical Dystonia

Cervical Dystonia

At baseline patients received incobotulinumtoxinA (Xeomin) or placebo. Thereafter, all patients who entered the extension period were treated with up to five injection sessions of incobotulinumtoxinA (Xeomin) during the extension period.

Completed21 enrollment criteria

Neurotoxin and Physical Therapy

Cervical Dystonia

This study aims to compare Botox injections without Physical Therapy sessions to Botox injections combined with Physical Therapy sessions for treatment of Cervical Dystonia. It is expected that Botox combined with Physical Therapy will improve Cervical Dystonia symptoms and quality of life more than Botox alone. It is also expected that Botox combined with Physical Therapy will enhance neuroplasticity, or the ability of the brain to make new connections, more than Botox alone at 4-5 weeks, and remain improved at 12 weeks, after Botox injection.

Completed5 enrollment criteria

An Open Label Safety and Immunogenicity Study of MYOBLOC (Neurobloc; Botulinum Toxin Type B) Injectable...

Cervical Dystonia

Five hundred patients with a confirmed clinical diagnosis of Cervical Dystonia (CD)are planned for enrollment into this open label study. These patients will be Type B toxin naive patients with CD. During this study patients will receive repeat injections of MYOBLOC when deemed appropriate by the Investigator. However, it will be recommended that injections occur not more frequently than every 12 weeks. Total duration of exposure to MYOBLOC will be targeted for at least two years, with potential exposure for up to 7 years in patients with earliest enrollment

Completed8 enrollment criteria
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