Active clinical trials for "Chronic Pain"

This is an open-label, long-term, multi-center multi-national post-marketing observational registry. The objective of this study is to monitor the long-term efficacy, safety, tolerability and quality of life outcomes associated with ziconotide (Prialt) and other analgesics utilized in the intrathecal (IT) management of severe chronic pain.

The objectives of this study are to evaluate the effectiveness, long-term safety, tolerability, satisfaction with treatment, and health-related quality of life (HRQoL) associated with Intrathecal PRIALT use for severe chronic pain of varying etiologies.

Background Chronic pain is one of the major health problems among Western countries. It is also one of the most frequent reasons for seeking medical care. Chronic pain is also an important problem in Hong Kong. A study conducted in our institution in 2002 discovered that the prevalence of chronic pain among Hong Kong adult population was 10.8%. This is expected to be higher after a decade as the population is aging because old age is one of the risk factors of chronic pain. The changes in prevalence, pattern, severity and help seeking behavior should be explored in order to evaluate the attitude toward chronic pain and the efficacy of chronic pain treatment. A local study reported the prevalence of chronic pain in 2007 in Hong Kong was as high as 34.9%. The reported rate was much higher than that of Ng et al. However, the difference in methodology produced different results even though they were done in the same population, which make the comparison difficult. Besides, the treatment efficacy and help seeking behavior were not studied in this study. The differences in mode of data collection, the wording of the questionnaire and the grouping of categories also influence the results of the study. It is also desirable to have the update information of chronic pain in Hong Kong regularly (i.e. every 5 years) in view of the rapid increase in prevalence of chronic pain in Hong Kong. To compare the changes in chronic pain prevalence and related outcomes, this study design is similar to the previous study done in our institution in 2002. The definition of chronic pain is the same as the previous study, which is pain persistence for 3 months or more. The mode of conducting the interview and the questionnaire used will be grossly similar to the previous study. Because chronic neuropathic pain is common and sometimes difficult to be managed, questions about the incidence of chronic neuropathic pain will also be sought. This important information has not been reported in Hong Kong before. The purpose of this study is to obtain the update cross-sectional prevalence and demographic information of chronic pain among Hong Kong adult population. The data will be compared with a similar study 4 done 10 years ago at our center in order to assess the change of chronic pain over the past decade. Treatment seeking preference will also be assessed. We hypothesize that the prevalence of chronic pain is increased when compare that of a decade ago.

The meta-analysis of data obtained from randomized controlled trial on effectiveness of radiofrequency denervation on reducing chronic neck and low back pain.

The purpose of this study is to understand the use of brief, personalized music interventions to decrease pain. Persisting and recurring pain is devastating to individuals and society. The worry and anxiety people feel while experiencing chronic pain may increase how much pain they feel. Enjoyable music feels good and affects brain chemicals in a way that can lessen feelings of pain. Music that feels good can also lower the anxiety and worry that accompany chronic pain which may play a role in the pain relief music provides.

The study will examine how medical cannabis use affects opioid analgesic use over time, with particular attention to THC/CBD content, HIV outcomes, and severe adverse events.

This is a proof of concept study to measure the effect of Wearable Health Technology (WHT), including the Apple Watch, iPhone, Pain App and Provider Dashboards on important clinical outcomes in patients treated for chronic pain. WHT will be tested in a group of chronic pain patients treated at a specialty pain clinic, the Geisinger Multidisciplinary Pain Program (MPP). Primary and secondary outcomes include pain, physical function, depression, pain medicine use, amount of sleep, activity levels, healthcare resource utilization and cost. The WHT will collect self-reported data on pain, pain management therapies, and medication utilization, and passively collected data on subject activity levels and sleep. Additional data will be collected on device utilization by patients and health care professionals.

The aim of this epidemiologic prospective study is to determine the prevalence of CPSP defined as pain occurring 4 months after scoliosis and thoracic surgery and rated > 3 on a 10 point visual analogue scale or FLACC scale, in children aged from 6 to 18 years. The main objective : prevalence of chronic post surgical pain 4 months after scoliosis ant thoracic surgery in children aged 6 to 18 years. The secondary objectives: the intensity of chronic post surgical pain, the prevalence of neuropathic syndrome and the predictive risk factors.

There is a significant debate whether local infiltration techniques may be a method to treat complicated chronic pain syndromes, e.g. refractory headache. Until now there is a lack of evidence regarding efficacy of this treatment especially in long term follow up. Similarly, indication and management are under debate. Aim of this trial is to analyse pain scores during first treatment with anaesthesiological infiltration series.

Chronic pain affects approximately 20% of adults, 50% of the elderly population and over 1.5 billion people worldwide. Societal and economic issues are also crucial, as 60% of people with pain are less able or unable to work and 20% say they have lost their jobs because of pain. The overall cost of chronic pain is estimated at around 300 billion euros in the EU. Unfortunately, current treatments for chronic pain have limited effectiveness. Pain clinics, which support the most complex and refractory cases of chronic pain, as well as general practitioners and patients expect improvements, both in terms of therapeutic efficacy and organization of care. In order to allow the characterization and a personalized follow-up of chronic pain patients, Investigator has created e-DOL, a smartphone application for patients and a web platform for physicians. The purpose of this study is to evaluate the feasibility and clinical interest of an e-Health smartphone application for the characterization and follow-up of chronic pain patients..