IMC-A12 in Treating Young Patients With Relapsed or Refractory Ewing Sarcoma/Peripheral Primitive...
Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal TumorUnspecified Childhood Solid Tumor1 moreThis phase I clinical trial is studying the side effects and best dose of IMC-A12 in treating young patients with relapsed or refractory Ewing sarcoma/peripheral primitive neuroectodermal tumor or other solid tumors. Monoclonal antibodies, such as IMC-A12, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or carry cancer-killing substances to them.
Ixabepilone in Treating Young Patients With Refractory Solid Tumors
Adult RhabdomyosarcomaAdult Synovial Sarcoma11 moreThis phase II trial is studying how well ixabepilone works in treating young patients with refractory solid tumors. Drugs used in chemotherapy, such as ixabepilone, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
Ispinesib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Lymphoma
Childhood Burkitt LymphomaChildhood Central Nervous System Germ Cell Tumor24 moreThis phase I trial is studying the side effects and best dose of ispinesib in treating young patients with relapsed or refractory solid tumors or lymphoma. Drugs used in chemotherapy, such as ispinesib, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing
Two Regimens of Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed Localized...
Ewing Sarcoma of BoneLocalized Ewing Sarcoma/Peripheral Primitive Neuroectodermal TumorThis clinical trial is studying the side effects of combination chemotherapy and to see how well they work in treating patients with newly diagnosed localized Ewing sarcoma family of tumors. Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) and giving the drugs in different ways may kill more tumor cells.
Oxaliplatin in Treating Young Patients With Recurrent Solid Tumors That Have Not Responded to Previous...
Childhood Central Nervous System Germ Cell TumorChildhood Extragonadal Germ Cell Tumor24 moreThis phase II trial is studying how well oxaliplatin works in treating young patients with recurrent solid tumors that have not responded to previous treatment. Drugs used in chemotherapy, such as oxaliplatin, work in different ways to stop tumor cells from dividing so they stop growing or die.
Tanespimycin in Treating Young Patients With Recurrent or Refractory Leukemia or Solid Tumors
Childhood Chronic Myelogenous LeukemiaChildhood Desmoplastic Small Round Cell Tumor12 moreThis phase I trial is studying the side effects and best dose of tanespimycin in treating young patients with recurrent or refractory leukemia or selected solid tumors. Drugs used in chemotherapy, such as tanespimycin, work in different ways to stop cancer cells from dividing so they stop growing or die.
FR901228 in Treating Children With Refractory or Recurrent Solid Tumors or Leukemia
Blastic Phase Chronic Myelogenous LeukemiaChildhood Central Nervous System Germ Cell Tumor24 moreThis phase I trial is studying the side effects and best dose of FR901228 in treating children with refractory or recurrent solid tumors or leukemia. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die
Oxaliplatin in Treating Children With Recurrent or Refractory Medulloblastoma, Supratentorial Primitive...
Brain and Central Nervous System TumorsRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of oxaliplatin in treating children who have recurrent or refractory medulloblastoma, supratentorial primitive neuroectodermal or atypical teratoid rhabdoid tumor.
Depsipeptide (Romidepsin) in Treating Patients With Metastatic or Unresectable Soft Tissue Sarcoma...
Adult Alveolar Soft-part SarcomaAdult Angiosarcoma18 moreThis phase II trial studies how well depsipeptide (romidepsin) works in treating patients with metastatic or unresectable soft tissue sarcoma. Drugs used in chemotherapy, such as depsipeptide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
Cilengitide in Treating Children With Refractory Primary Brain Tumors
Childhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus Tumor24 moreThis phase I trial is studying the side effects and best dose of cilengitide in treating children with recurrent, progressive, or refractory primary CNS tumors. Cilengitide may slow the growth of brain cancer cells by stopping blood flow to the tumor.